Romans 1:31 without understanding, covenant breakers, without natural affection, unforgiving, unmerciful”.
2 Timothy 3:3 “without natural affection, unforgiving, slanderers, without self-control, fierce, no lovers of good”.
“Natural affection” is to cherish affectionately one’s own family, kin and race. Scripture calls a lack of this heartless, hard hearted and a debased mind.